Subscribe to RSS Feed
News Newsfeeds Predictors for good functional outcome after neurocritical care
Written by Critical Care
There are only limited data on the long-term outcome of patients receiving specialized neurocritical care. In this study we analyzed survival, long-term mortality and functional outcome after neurocritical care and determined predictors for good functional outcome.
Methods:
We retrospectively investigated 796 consecutive patients admitted to a non-surgical neurologic intensive care unit over a period of two years (2006-2007). Demographic and clinical parameters were analyzed. Depending on the diagnosis we grouped patients according to their diseases (cerebral ischemia, intracranial hemorrhage (ICH), subarachnoid hemorrhage (SAH), meningitis/encephalitis, epilepsy, Guillain-Barre syndrome (GBS) and myasthenia gravis (MG), neurodegenerative diseases and encephalopathy, cerebral neoplasm and intoxication). Clinical parameters, mortality and functional outcome of all treated patients were analyzed. Functional outcome (using the modified Rankin Scale, mRS) one year after discharge was assessed by a mailed questionnaire or telephone interview. Outcome was dichotomized into good (mRS [less than or equal to]2) and poor (mRS [greater than or equal to]3). Logistic regression analyses were calculated to determine independent predictors for good functional outcome.
Results:
Overall in-hospital mortality amounted to 22.5% of all patients, and a good long-term functional outcome was achieved in 28.4%. The parameters age, length of ventilation, admission diagnosis of ICH, GBS/MG, and inoperable cerebral neoplasm as well as TISS-28 on day one were independently associated with functional outcome after one year.
Conclusions:
This investigation revealed that age, length of ventilation and TISS-28 on day one were strongly predictive for outcome. The diagnoses of hemorrhagic stroke and cerebral neoplasm leading to neurocritical care predispose for functional dependence or death, whereas patients with GBS and MG are more likely to recover after neurocritical care.
Monday, 19 July 2010 19:00
Introduction:There are only limited data on the long-term outcome of patients receiving specialized neurocritical care. In this study we analyzed survival, long-term mortality and functional outcome after neurocritical care and determined predictors for good functional outcome.
Methods:
We retrospectively investigated 796 consecutive patients admitted to a non-surgical neurologic intensive care unit over a period of two years (2006-2007). Demographic and clinical parameters were analyzed. Depending on the diagnosis we grouped patients according to their diseases (cerebral ischemia, intracranial hemorrhage (ICH), subarachnoid hemorrhage (SAH), meningitis/encephalitis, epilepsy, Guillain-Barre syndrome (GBS) and myasthenia gravis (MG), neurodegenerative diseases and encephalopathy, cerebral neoplasm and intoxication). Clinical parameters, mortality and functional outcome of all treated patients were analyzed. Functional outcome (using the modified Rankin Scale, mRS) one year after discharge was assessed by a mailed questionnaire or telephone interview. Outcome was dichotomized into good (mRS [less than or equal to]2) and poor (mRS [greater than or equal to]3). Logistic regression analyses were calculated to determine independent predictors for good functional outcome.
Results:
Overall in-hospital mortality amounted to 22.5% of all patients, and a good long-term functional outcome was achieved in 28.4%. The parameters age, length of ventilation, admission diagnosis of ICH, GBS/MG, and inoperable cerebral neoplasm as well as TISS-28 on day one were independently associated with functional outcome after one year.
Conclusions:
This investigation revealed that age, length of ventilation and TISS-28 on day one were strongly predictive for outcome. The diagnoses of hemorrhagic stroke and cerebral neoplasm leading to neurocritical care predispose for functional dependence or death, whereas patients with GBS and MG are more likely to recover after neurocritical care.
Authors: Ines Kiphuth
Read More: Critical Care - Latest Articles
You need to login or register to post comments.
E - CC WORK PROGRAMME 10-11
ARFSeminarflyer