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- Is passive leg raising safe in mechanically ventilated patients receiving enteral nutrition?
- Promising prognostic potentials: Perhaps *
- Phase II trial on the use of Dextran 70 or starch for supportive therapy in Kenyan children with severe malaria *
- A history of resolving conflicts over end-of-life care in intensive care units in the United States *
- Cold aortic flush and chest compressions enable good neurologic outcome after 15 mins of ventricular fibrillation in cardiac arrest in pigs *
- Response from the Editor-in-Chief of Critical Care Medicine
- Therapeutic strategies for severe acute lung injury
- Defining death in donation after circulatory determination of death protocols: A bluish shade of violet
- A survival benefit of combination antibiotic therapy for serious infections associated with sepsis and septic shock is contingent only on the risk of death: A meta-analytic/meta-regression study
- Biomarkers as end points in clinical trials of severe sepsis: A garden of forking paths *
- Vancomycin plus rifampicin for methicillin-resistant Staphylococcus aureus pneumonia benefits only those who have no development of rifampicin resistance during treatment
- Is heart period variability associated with the administration of lifesaving interventions in individual prehospital trauma patients with normal standard vital signs? *
- Lazarus phenomenon, autoresuscitation, and nonheart-beating organ donation
- Validity and reliability of an intuitive conscious sedation scoring tool: The nursing instrument for the communication of sedation *
- Breathing requirement and metabolic rate during cardiopulmonary resuscitation: Cardiac arrest during exercise
- A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis *
- Acute pulmonary hypertension: What is wrong on the right?: Erratum
- Acute renal failure is NOT an "acute renal success"-a clinical study on the renal oxygen supply/demand relationship in acute kidney injury
- Communication of sedation in the intensive care unit: Is it the real issue? *
- Patients with acute pancreatitis complicated by organ failure show highly aberrant monocyte signaling profiles assessed by phospho-specific flow cytometry *
- Once bitten, twice shy: Defective monocyte signaling in acute pancreatitis *
- Quantitative assessment of somatosensory-evoked potentials after cardiac arrest in rats: Prognostication of functional outcomes *
- Role of regulatory T cells in long-term immune dysfunction associated with severe sepsis
- Financial disclosures in clinical practice guidelines
- Cerebral effects of hyperglycemia in experimental cardiac arrest
- Predicting dead space ventilation in critically ill patients using clinically available data
- Bone marrow-derived mononuclear cell therapy in experimental pulmonary and extrapulmonary acute lung injury
- Futility in the intensive care unit: Hard cases make bad law *
- Mechanical ventilation can cause changes in pulmonary circulation
- Severe malaria and sepsis: Will one fluid strategy suit both? *
- This is cool! Hypothermia, chest compressions, and ventilation can be accomplished in a large animal cardiac arrest model: Paving the way to human clinical trials *
- Nursing implications for prevention of adverse drug events in the intensive care unit: Erratum
- Half empty or half full? *
- Probiotics to prevent ventilator-associated pneumonia: No robust evidence from randomized controlled trials: Erratum
- Quality of life in patients aged 80 or over after intensive care unit discharge
- Retrospective agreement and consent to neurocritical care is influenced by functional outcome
- Simvastatin attenuates ventilator-induced lung injury in mice
- Concepts in hypoxia reborn
- Corticosteroids for sepsis: registry versus the Cochrane systematic review!
- Is routine autopsy in the intensive care unit viable? Authors' response
- Early administration of norepinephrine increases cardiac preload and cardiac output in septic patients with life-threatening hypotension
- Bedside quantification of dead-space fraction using routine clinical data in patients with acute lung injury: secondary analysis of two prospective trials
- Alpha-2 agonists and sepsis: improved survival?
- Cerebral microcirculation is impaired during sepsis: an experimental study
- Analytic Reviews: Managing the Agitated Patient in the ICU: Sedation, Analgesia, and Neuromuscular Blockade
- Induced Hypothermia for Trauma: Current Research and Practice
- Book Review: Book Review: Peter Kohl, Frederick Sachs, and Michael Franz Cardiac Mechano-Electric Feedback and Arrhythmias: From Pipette to Patient St Louis, MO: Elsevier Saunders, 2005. 423 pp. ISBN: 1-4160-0034-8
- Review of a Large Clinical Series: The Value of Routinely Obtained Chest Radiographs on Admission to a Mixed Medical--Surgical Intensive Care Unit
- The Yin and Yang of Hypothermia in Trauma
- The Impact of a ''Low-Intensity'' Versus ''High-Intensity'' Medical Intensive Care Unit on Patient Outcomes in Critically Ill Veterans
- Posttraumatic Stress Disorder in Cancer ICUs
- Assessment of monocytic HLA-DR expression in ICU patients: analytical issues for multicentric flow cytometry studies
- To transfuse or not to transfuse: thinking outside the Box
- APCAP - activated protein C in acute pancreatitis: a double-blind randomized human pilot trial
- Correction: Extravascular lung water index measurement in critically ill children does not correlate with a chest x-ray score of pulmonary edema
- Standardized intensive care unit management in an anhepatic pig model: new standards for analyzing liver support systems
- Atrial fibrillation is not just an artefact n ICU
- Positive end-expiratory pressure affects the value of intra-abdominal pressure in acute lung injury/acute respiratory distress syndrome patients: a pilot study
- Does low angiopoietin-1 predict adverse outcome in sepsis?
- Predictors for good functional outcome after neurocritical care
- Macrolides and community-acquired pneumonia: is quorum sensing the key?
- Sepsis-Related Stress Response: Known Knowns, Known Unknowns, and Unknown Unknowns
- Hot Times in the ICU
- Improving surgical outcomes: it's the destination not the journey
- Computed tomography assessment of exogenous surfactant-induced lung reaeration in patients with acute lung injury
- The dilemma of good clinical practice in the study of compromised standards of care
- Physicians' and nurses' opinions on selective decontamination of the digestive tract and selective oropharyngeal decontamination: a survey
- Updating the evidence for the role of corticosteroids in severe sepsis and septic shock: a Bayesian meta-analytic perspective
- Up regulation of the pro-apoptotic genes BID and FAS in septic shock patients
- Electrical muscle stimulation for prevention of critical illness polyneuropathy
- Pulse pressure analysis: to make a long story short
- Proven infection-related sepsis induces a differential stress response early after ICU admission
- Bench-to-bedside review: Chloride in critical illness
- A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes
- Hemodynamic changes during weaning: can we assess and predict cardiac related weaning failure by transthoracic echocardiography?
- Another explanation of decreased oxygen consumption in lactic acidosis
- Time course of nitric oxide synthases, nitrosative stress, and poly(ADP ribosylation) in an ovine sepsis model
- The role for autopsy in the intensive care unit: technological considerations
- Commonly applied positive end-expiratory pressures do not prevent functional residual capacity decline in the setting of intra-abdominal hypertension: a pig model
- Limits of surrogate decision making
- Critical care medicine growth requires dealing with our "perfect storm" of manpower shortage
- Nurse staffing and patient outcomes in critical care: A concise review
- Education is what remains after medical emergency teams are trained
- N-methyl-D-aspartate limbic encephalitis: Diagnosis should respect well-recognized criteria
- Human immunodeficiency virus infection and hospital mortality in acute lung injury patients
- Delirium as a predictor of long-term cognitive impairment in survivors of critical illness
- Mini-bronchoalveolar lavage quantitative polymerase chain reaction for diagnosis of methicillin-resistant Staphylococcus aureus pneumonia *
- The intensive care delirium screening checklist has many potential benefits over the nursing delirium screening scale
- Microvascular hemodynamics in human hypothermic circulatory arrest and selective antegrade cerebral perfusion
- Determination of decision-making capacity: A first step
- Health-related quality of life and return to work after critical illness in general intensive care unit patients: A 1-year follow-up study
- Intensive care unit-acquired weakness
- Extracranial injuries are important in determining mortality of neurotrauma *
- Temperature monitored on the cuff surface of an endotracheal tube reflects body temperature
- Fat and the gut: More than empty calories *
- Septic shock and nonpulmonary organ dysfunction in pneumonic plague: The role of Yersinia pestis pCD1- vs. pgm- virulence factors
- Dry powder aerosolization of a recombinant surfactant protein-C-based surfactant for inhalative treatment of the acutely inflamed lung *
- Cortisol variation after low-dose Cortrosyn test
- Protection against early intestinal compromise by lipid-rich enteral nutrition through cholecystokinin receptors *
- Severe hypercortisolism: A medical emergency requiring urgent intervention
- Broadening horizons: Research priorities in pneumonia *
- Probiotics to prevent ventilator-associated pneumonia: No robust evidence from randomized controlled trials
- Preserved cerebral coupling and cerebrovascular reactivity after cardiac arrest: Lessons learned in the era of therapeutic hypothermia *
- Prognostic models: Are these models health fortune-telling tools? *
- Farewell to exogenous surfactant therapy in acute lung injury/acute respiratory distress syndrome! Or, must we start all over again? *
- Clinical practice guidelines: Red blood cell transfusion in adult trauma and critical care: Erratum
- Preserved metabolic coupling and cerebrovascular reactivity during mild hypothermia after cardiac arrest *
- Continuing Medical Education Questions
- Increased duration of mechanical ventilation is associated with decreased diaphragmatic force: a prospective observational study
- Do recruitment maneuvers simply improve oxygenation?
- Homeostatic control mechanisms
- Protective mechanisms of the body
- Antenatal anaesthetic assessment of the pregnant woman
- Starvation, exercise, injury and obesity
- Pre-eclampsia and the anaesthetist
- Intrauterine fetal resuscitation
- Hormonal control of metabolism: regulation of plasma glucose
- Analgesia in labour: induction and maintenance
- Physiology of ageing
- Non-neuraxial analgesia during labour
- Editorial Board
- Contents
- MCQs
- Clinical review: Considerations for the triage of maternity care during an influenza pandemic - one institution's approach
- Red cell transfusion triggers in critically ill patients: time for some new TRICCs?
- Spontaneous hypothermia on intensive care unit admission is a predictor of unfavorable neurological outcome in patients after resuscitation: an observational cohort study
- Echocardiography: a help in the weaning process
- Bending the cost curve in the United States: The role of comparative effectiveness research
- Ethics roundtable debate: Open-ended ICU care - can we afford it?
- Immune status in sepsis: the bug, the site of infection and the severity can make the difference
- Risk factors in critical illness myopathy during the early course of critical illness: a prospective observational study
- Dirty mouth? Should you clean it out? Decontamination for the prevention of pneumonia and mortality in the ICU
- Ventilation inhomogeneity is one criterion among many in multidimensional PEEP titration
- A plethora of angiopoietin-2 effects during clinical sepsis ?
- Intraoperative fluid optimization using stroke volume variation in high risk surgical patients: results of prospective randomized study
- Pathophysiology of septic encephalopathy - an unsolved puzzle
- Model of end stage liver disease (MELD) score greater than 23 predicts length of stay in the ICU but not mortality in liver transplant recipients
- In-hospital percentage BNP reduction is highly predictive for adverse events in patients admitted for acute heart failure: the Italian RED Study
- Dramatic increase of third-generation cephalosporin resistant E. coli in German intensive care units: secular trends in antibiotic drug use and bacterial resistance, 2001-2008
- Kinetics of plasmatic cytokines and cystatin C during and after hemodialysis in septic shock-related acute renal failure
- Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury
- How the relationships between general practitioners and intensivists can be improved: the general practitioners' point of view
- The complex interplay between delirium, sepsis and sedation
- Pulse pressure variation and hemodynamic response in patients with elevated pulmonary artery pressure: a clinical study
- CD4+ lymphocyte adenosine triphosphate determination in sepsis: a cohort study
- Arterial pressure-based cardiac output in septic patients: different accuracy of pulse contour and uncalibrated pressure waveform devices
- Incidence and prognostic impact of new onset atrial fibrillation in patients with septic shock: a prospective observational study
- Survival trends in critically ill HIV-infected patients in the highly active antiretroviral therapy era
- Another step for the noninvasive ventilation in COPD patients !
- Extravascular lung water index measurement in critically ill children does not correlate with a chest X-ray score of pulmonary edema
- Underpowered trials in critical care medicine: how to deal with it?
- Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections
- Do we need a critical care ultrasound certification program? Implications from an Australian medical-legal perspective
- Strict or loose glycemic control in critically ill patients - implementing the best available evidence from randomized controlled trials
- Severe endothelial injury and subsequent repair in patients after successful cardiopulmonary resuscitation
- Possible life threatening adverse reaction to monovalent H1N1 vaccine
- Preoperative diastolic function predicts the onset of left ventricular dysfunction following aortic valve replacement in high-risk patients with aortic stenosis
- Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts
- Global utilization of low-dose corticosteroids in severe sepsis and septic shock: a report from the PROGRESS registry
- Hyperlactataemia in critical illness and cardiac surgery
- Traditional Transfusion Practices are Changing
- Cardiac Tamponade in a Patient With Dengue Fever and Lupus Nephritis: A Case Report
- Extracorporeal Removal Techniques for the Poisoned Patient: A Review for the Intensivist
- Use of a Helium-Oxygen Mixture to Facilitate Ventilation During Bronchoscopy Through a Laryngeal Mask Airway
- Review of a Large Clinical Series: Structure, Process, and Outcome of all Intensive Care Units Within the Province of British Columbia, Canada
- Analytic Reviews: Prevention of Central Venous Catheter Bloodstream Infections
- A Descriptive Analysis of Patients Admitted to the Intensive Care Unit of the 10th Combat Support Hospital Deployed in Ibn Sina, Baghdad, Iraq, From October 19, 2005, to October 19, 2006
- Pancreatitis Associated With Strongyloides stercoralis Infection in a Patient Chronically Treated With Corticosteroids
- The Utility of Tissue Doppler Imaging for the Noninvasive Determination of Left Ventricular Filling Pressures in Patients With Septic Shock
- Regional ICU Care: The Future is Now
- Transoesophageal echocardiography in cardiac anaesthesia
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